A validated stability indicating RP-HPLC method for the determination of molnupiravir in pharmaceutical dosage form

A simple, Precise, Accurate method was developed for the estimation of Molnupiravirby RP-HPLC technique. Chromatographic conditions used are stationary phase Agilent C18 (250 mm*4.6mm3.6m), Mobile Orthophopoaricacid: Acetonitrile in ratio 60:40 and flow rate maintained at 1.0 mL/min, detection wave length 254 nm, column temperature set to 30o C diluent mobile Conditions were finalized as optimized method. System suitability parameters studied by injecting standard six times results well under acceptance criteria. The retention time Molnupiravir 2.46 min. validated linearity, accuracy, precision, specificity, limit detection, quantification robustness. Limit found 0.06 ?g/ml 0.21 respectively recovery from tablet formulation 99.73%. proposed successfully applied quantitative determination formulation.